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April 27, 2003
Open Bioinformatics
Creating a bioinformatics nation
The Open Bioinformatics Foundation
Lincoln Stein wrote this as a keynote speech for the 2002 O'Reilly Open Bioinformatics Conference in Tucson, Arizona. It later appeared in Nature, where I read it last year. It reminded me of my own experiences and the financial software industry's travails over the last 20 years which I have written about in this very blog.
A web-services model will allow biological data to be fully exploited.
During the Middle Ages and early Renaissance, Italy was fragmented into dozens of rival city-states controlled by such legendary families as the Estes, Viscontis and Medicis. Though picturesque, this political fragmentation was ultimately damaging to science and commerce because of the lack of standardization in everything from weights and measures to the tax code to the currency to the very dialects people spoke. A fragmented and technologically weak society was vulnerable to conquest, and from the seventeenth to the nineteenth centuries Italy was dominated by invading powers.
The old city-states of Italy are an apt metaphor for bioinformatics today. The field is dominated by rival groups, each promoting its web sites, services and data formats. Unarguably, this environment of creative chaos has greatly enriched the field. But it has also created a significant hindrance to researchers wishing to exploit the wealth of genome data to its fullest.
Despite its shaky beginning, the nation of Italy was eventually forged through a combination of violent and diplomatic efforts. It is now a strong and stable component of a larger economic unit, the European Union, with which it shares a common currency, a common set of weights and measures, and a common set of rules for national and international commerce. My hope is that bioinformatics will one day achieve the same degree of strength and stability by adopting a universal code of conduct along the lines I propose here.
Read more of Lincoln's article for his hopes of salvation, but I'm not giving too much away if I direct you to the Open Bioinformatics Foundation website ...
Posted by daen at April 27, 2003 12:17 AM